Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butetamate SCHEMBL317018 | 0.78 | KDM4E (1.00) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| Butamirate SCHEMBL636120 | 0.74 | KDM4E (0.88) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL8508561 | 0.74 | KDM4E (0.47) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| Citric Acid SCHEMBL27486294 | 0.72 | KDM4E (0.58) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| Citric Acid SCHEMBL9323612 | 0.71 | CHRM1 (0.60) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| Alverine SCHEMBL352008 | 0.70 | KDM4E (1.00) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL2441378 | 0.70 | KDM4E (0.60) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL6942126 | 0.69 | KDM4E (0.48) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL9323620 | 0.69 | CYP2D6 (0.47) | KDM4EMAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL11578611 | 0.68 | NPC1 (0.48) | LMNAALDH1A1TSHRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308735-A | Aromatic-aldehyde resins, improved solubility | NIPPON PAINT CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0540016-A1 | Photosensitive resin and resin composition for lithographic printing | Nippon Paint Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |