SCHEMBL9325691

SCHEMBL9325691

CCCCCCC(Cc1ccccc1-c1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
FOLH1 Q04609 2/20 0.51
PPARA Q07869 2/20 0.48
PTGES O14684 2/20 0.47
ALOX5 P09917 2/20 0.47
PPARG P37231 2/20 0.47
SOAT1 P35610 2/20 0.46
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
MMP2 P08253 9/20 0.44
MMP1 P03956 4/20 0.44
MMP3 P08254 4/20 0.44
GRIK1 P39086 1/20 0.43
GRIK2 Q13002 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327562 0.87 MMP2 (0.45) KMT2AFOLH1PPARAPTGESALOX5
SCHEMBL10458467 0.87 KMT2A (0.46) KMT2AFOLH1PPARAPTGESALOX5
SCHEMBL6724651 0.85 KMT2A (0.71) KMT2AFOLH1PPARAPPARGMME
Hydrochloric Acid SCHEMBL6721519 0.84 KMT2A (0.69) KMT2AFOLH1PPARAPPARGMME
SCHEMBL6721538 0.83 KMT2A (0.59) KMT2AFOLH1MMEACECPA1
SCHEMBL1582615 0.82 KMT2A (0.67) KMT2AFOLH1PPARAPPARGMME
SCHEMBL28807900 0.82 FOLH1 (0.52) FOLH1PPARAPTGESALOX5PPARG
SCHEMBL20531033 0.81 PPARG (0.42) KMT2AFOLH1PPARAPTGESALOX5
SCHEMBL20531034 0.81 PPARG (0.42) KMT2AFOLH1PPARAPTGESALOX5
SCHEMBL20531036 0.81 PPARG (0.42) KMT2AFOLH1PPARAPTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342666-B1 Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same NIPPON MINING CO (JP) 1994-03-09 EP disclosed
US-4970023-A Biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switch elements each containing the same NIPPON MINING CO., LTD. (JP) 1990-11-13 US disclosed
EP-0342666-A2 Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same JAPAN ENERGY CORPORATION (JP) 1989-11-23 EP disclosed