Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325691 | 0.87 | KMT2A (0.56) | MMP2PPARAFOLH1KMT2APPARG | |
| SCHEMBL9327554 | 0.85 | PPARA (0.52) | MMP2MMP9MMP12PPARAPPARG | |
| SCHEMBL10458467 | 0.82 | KMT2A (0.46) | MMP2PPARAFOLH1KMT2APPARG | |
| SCHEMBL9326090 | 0.81 | KMT2A (0.49) | MMP2MMP9MMP12PPARAKMT2A | |
| SCHEMBL9717228 | 0.80 | NPC1 (0.51) | MMP2MMP9MMP12KMT2APTGES | |
| SCHEMBL9717225 | 0.80 | ACE2 (0.50) | MMP2MMP9MMP12KMT2AACE2 | |
| SCHEMBL1195165 | 0.78 | CES2 (0.51) | MMP2MMP9MMP12ACE2PRSS1 | |
| SCHEMBL6684015 | 0.78 | CES2 (0.51) | MMP2MMP9MMP12ACE2PRSS1 | |
| SCHEMBL8901194 | 0.78 | CES2 (0.51) | MMP2MMP9MMP12ACE2PRSS1 | |
| SCHEMBL6686403 | 0.78 | CES2 (0.51) | MMP2MMP9MMP12ACE2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342666-B1 | Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same | NIPPON MINING CO (JP) | 1994-03-09 | — | — | EP | disclosed |