Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | ME3 | Q16798 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KLK1 | P06870 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23130338 | 0.85 | POLB (1.00) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL15652941 | 0.85 | RAB9A (0.73) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL30662307 | 0.85 | SMN1; SMN2 (0.74) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL23686078 | 0.85 | NPC1 (0.73) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL25893862 | 0.85 | RAB9A (0.73) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL5051924 | 0.84 | EPHX2 (1.00) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL3397254 | 0.84 | EPHX2 (1.00) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL19254905 | 0.83 | SMN1; SMN2 (0.72) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL19254904 | 0.83 | NPC1 (0.71) | NPC1RAB9APOLBEPHX2KMT2A | |
| SCHEMBL5053663 | 0.83 | RAB9A (0.71) | NPC1RAB9APOLBEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |