Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18307122 | 0.93 | LMNA (0.69) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL5053663 | 0.83 | RAB9A (0.71) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL19254905 | 0.83 | SMN1; SMN2 (0.72) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL9325905 | 0.83 | NPC1 (1.00) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL2753089 | 0.82 | EPHX2 (0.96) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL23130338 | 0.81 | POLB (1.00) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL15652941 | 0.81 | RAB9A (0.73) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL30662307 | 0.81 | SMN1; SMN2 (0.74) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL23686078 | 0.81 | NPC1 (0.73) | NPC1RAB9APOLBEPHX2ALDH1A1 | |
| SCHEMBL25893862 | 0.81 | RAB9A (0.73) | NPC1RAB9APOLBEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247976-B2 | Synthetic ligands that modulate the activity of the RhlR quorum sensing receptor | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-02-15 | — | — | US | disclosed |
| US-10322112-B2 | Compound combinations for attenuation of bacterial virulence | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
| US-20190144407-A1 | Synthetic Ligands that Modulate the Activity of the RhlR Quorum Sensing Receptor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-05-16 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | PNISR, PGLS, QRFPR | NPC1 4739/4885RAB9A 127/4885POLB 3661/4885 |
| US-20190144407-A1 | Synthetic Ligands that Modulate the Activity of the RhlR Quorum Sensing Receptor | AREG, QRFPR, GPR139 | NPC1 4867/4885RAB9A 2846/4885POLB 4226/4885 |
| US-10322112-B2 | Compound combinations for attenuation of bacterial virulence | PNISR, BLVRB, PGLS | NPC1 4653/4885RAB9A 286/4885POLB 3787/4885 |
| US-11247976-B2 | Synthetic ligands that modulate the activity of the RhlR quorum sensing receptor | AREG, QRFPR, GPR139 | NPC1 4867/4885RAB9A 2846/4885POLB 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.