Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327367 | 0.87 | LMNA (0.55) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL9328668 | 0.79 | SMN1; SMN2 (0.42) | MAPTL3MBTL1SMN1; SMN2LMNANPC1 | |
| SCHEMBL9328352 | 0.79 | NPC1 (0.39) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL30070877 | 0.77 | ABCB1 (0.40) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL9327326 | 0.77 | CLCN2 (0.41) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL3277622 | 0.76 | CA1 (0.57) | SMN1; SMN2HTTNPC1RAB9ACTSD | |
| SCHEMBL7643473 | 0.75 | LMNA (0.42) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL12375199 | 0.74 | ACHE (0.65) | MAPTL3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL12408754 | 0.74 | ACHE (0.65) | MAPTL3MBTL1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL2047965 | 0.73 | LMNA (0.38) | SMN1; SMN2HTTLMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403026-B1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5071465-A | Preemergence; postemergence | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| US-4999448-A | ALKYLATION WITH PHENYLTHIOMETHYL LITHIUM COMPOUND, CYCLIZATION, INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |