Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 4/20 | 1.00 |
| ▸ | MAOB | P27338 | 13/20 | 0.79 |
| ▸ | MAOA | P21397 | 7/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA4 | P22748 | 2/20 | 0.73 |
| ▸ | CA7 | P43166 | 2/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023219 | 0.90 | SLC16A3 (0.82) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL28374375 | 0.90 | SLC16A3 (0.81) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL4758088 | 0.90 | SLC16A3 (0.81) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL93300 | 0.89 | MAOB (0.85) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL28373994 | 0.89 | SLC16A3 (0.80) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL17704685 | 0.89 | SLC16A3 (0.80) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL17701087 | 0.89 | SLC16A3 (1.00) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL16398257 | 0.88 | MAOB (0.79) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL28373419 | 0.88 | MAOB (1.00) | SLC16A3MAOBMAOACA12CA1 | |
| SCHEMBL28374663 | 0.88 | SLC16A3 (0.79) | SLC16A3MAOBMAOACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | claimed |
| CN-1244573-C | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2006-03-08 | — | — | CN | claimed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | claimed |
| CN-1445222-A | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2003-10-01 | — | — | CN | claimed |
| CN-110804045-B | Coumarin hybrid pyridone amide derivative with potential anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110804045-A | Coumarin hybrid pyridone amide derivative with potential anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2020-02-18 | — | — | CN | disclosed |
| EP-2611912-B1 | NOVEL MONOOXYGENASE VARIANTS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2611912-B1 | NOVEL MONOOXYGENASE VARIANTS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| EP-2611912-A2 | NOVEL MONOOXYGENASE VARIANTS | B.R.A.I.N. Biotechnology Research and Information Network AG (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2426198-A1 | Cytochrome P450 monooxygenase variants | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | disclosed |
| CN-1244573-C | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2006-03-08 | — | — | CN | disclosed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | disclosed |
| CN-1445222-A | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2003-10-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | SLC16A3, SLC16A1, SLC16A8 | SLC16A3 1/4885MAOB 3418/4885MAOA 3542/4885 |
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SLC5A2, CYP2D6, IAPP | SLC16A3 2784/4885MAOB 804/4885MAOA 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.