Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327826 | 0.88 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL4138316 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL20349587 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL9325952 | 0.84 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL20349586 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL3928629 | 0.84 | CNR2 (0.50) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL9080033 | 0.83 | CES2 (0.46) | MTNR1BCES2CES1LMNAMTNR1A | |
| SCHEMBL9076689 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL2011761 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL4856143 | 0.82 | PARP1 (0.50) | L3MBTL1CES2CES1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298511-A | Alkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-29 | — | — | US | disclosed |
| EP-0540165-A1 | Alkanoic acid derivatives | ZENECA LIMITED (GB) | 1993-05-05 | — | — | EP | disclosed |