Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638536 | 0.80 | NQO1 (0.61) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL19808351 | 0.75 | PLK1 (0.60) | MAPK1PLK1ROCK2CHEK2GSK3A | |
| SCHEMBL9514574 | 0.74 | NQO1 (0.70) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL49554 | 0.74 | NQO1 (0.70) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL7598100 | 0.70 | GAA (0.49) | MAPTPOLB | |
| SCHEMBL8870928 | 0.70 | POLB (0.60) | MAPTL3MBTL1LMNAADAMTS5POLB | |
| SCHEMBL8725864 | 0.68 | NQO1 (0.54) | KDM4EMAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL18826799 | 0.68 | NQO1 (0.54) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL19019509 | 0.68 | KMT2A (0.49) | KDM4EMAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL9620305 | 0.68 | KDM4E (0.52) | KDM4EMAPTALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6092915-A | — | — | None | — | — | JP | disclosed |
| JP-H0692915-A | 1,2-DIAMINOCYCLOBUTENE-3,4-DIONE DERIVATIVE AND ITS USE | SUMITOMO METAL IND LTD | 1994-04-05 | — | — | JP | disclosed |