Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326649 | 1.00 | FAAH (0.43) | FAAHTRPV1MEN1KMT2ATDP1 | |
| SCHEMBL9328599 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL8023742 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9325525 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9325532 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9225064 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL8023741 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9325631 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9225054 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR | |
| SCHEMBL9328601 | 0.98 | FAAH (0.47) | FAAHTRPV1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361157-B1 | Phenyl pyridines | HOFFMANN LA ROCHE (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5284956-A | Liquid crystalline mixtures containing 2-(2-fluorophenyl) pyridines | HOFFMANN-LA ROCHE INC. (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0228303-B1 | FERROELECTRIC PYRIDINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0239403-B1 | 2-(4'-ALKOXYPHENYL)-5-ALKYLPYRIDINES | Chisso Corporation (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0361157-A1 | Phenyl pyridines | F. HOFFMANN-LA ROCHE AG (CH) | 1990-04-04 | — | — | EP | disclosed |
| US-4795587-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4784792-A | OPTICAL DISPLAYS, LIGHT SWITCHES | CHISSO CORPORATION (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0239403-A1 | 2-(4'-Alkoxyphenyl)-5-alkylpyridines | Chisso Corporation (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0228303-A1 | Ferroelectric pyridine compounds and liquid crystal compositions containing them | Chisso Corporation (JP) | 1987-07-08 | — | — | EP | disclosed |