Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491075 | 0.81 | USP2 (0.34) | MEN1KMT2AHSD17B10HTTALDH1A1 | |
| SCHEMBL10472943 | 0.78 | KDM4E (0.34) | MEN1KMT2AHSD17B10HTTALDH1A1 | |
| SCHEMBL2211488 | 0.76 | POLB (0.41) | MEN1KMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL2589900 | 0.75 | MEN1 (0.51) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL157807 | 0.75 | MEN1 (0.51) | MEN1KMT2ACASP1BRCA1CASP7 | |
| Bromide SCHEMBL10687133 | 0.73 | MEN1 (0.50) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL11342834 | 0.73 | CES1 (0.49) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6274683 | 0.71 | MEN1 (0.41) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL720769 | 0.69 | NPC1 (0.50) | MEN1KMT2ACASP1BRCA1CASP7 | |
| Piperazine SCHEMBL28177083 | 0.69 | MEN1 (0.48) | MEN1KMT2ACASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257433-B1 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID CO (US) | 1994-03-23 | — | — | EP | disclosed |
| US-4757146-A | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0257433-A2 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |