Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342834 | 0.81 | CES1 (0.49) | GSK3BALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9491075 | 0.79 | USP2 (0.34) | POLBGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL10472943 | 0.77 | KDM4E (0.34) | POLBGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL11260189 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL11503456 | 0.76 | MAOA (0.34) | HPGD | |
| SCHEMBL9326734 | 0.76 | MEN1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL9516833 | 0.75 | ALDH1A1 (0.35) | GSK3BALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3346448 | 0.74 | CXCR2 (0.34) | POLBALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30824783 | 0.74 | ALDH1A1 (0.38) | POLBGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL7540808 | 0.73 | AR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120323018-A1 | Preparation of Monomers for Grafting to Polyolefins, and Lubricating Oil Compositions Containing Grafted Copolymer | GOLDBLATT IRWIN L (US) | 2012-12-20 | — | — | US | claimed |
| US-7981847-B2 | Dispersant viscosity index improvers comprising a polyolefin grafted with an unsaturated amide formed by the acylation of an amine by an unsaturated acid; raising the viscosity index of the base oil by at least about 5 points;keeping insoluble materials in the crankcase of an internal combustion engine | CASTROL LIMITED (GB) | 2011-07-19 | — | — | US | claimed |
| EP-1513794-A4 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LTD (GB) | 2008-09-10 | — | — | EP | claimed |
| EP-1513794-A2 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LIMITED (GB) | 2005-03-16 | — | — | EP | claimed |
| US-20040043909-A1 | Preparation of monomers for grafting to polyolefins, and lubricating oil compositions containing grafted copolymer | CASTROL LIMITED (GB) | 2004-03-04 | — | — | US | claimed |
| WO-2003099890-A2 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LIMITED (GB) | 2003-12-04 | — | — | WO | claimed |
| EP-1513794-B1 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LTD (GB) | 2013-03-06 | — | — | EP | disclosed |
| US-20120323018-A1 | Preparation of Monomers for Grafting to Polyolefins, and Lubricating Oil Compositions Containing Grafted Copolymer | GOLDBLATT IRWIN L (US) | 2012-12-20 | — | — | US | disclosed |
| EP-2484660-A2 | Preparation of monomers for grafting to polyolefins | Castrol Limited (GB) | 2012-08-08 | — | — | EP | disclosed |
| US-7981847-B2 | Dispersant viscosity index improvers comprising a polyolefin grafted with an unsaturated amide formed by the acylation of an amine by an unsaturated acid; raising the viscosity index of the base oil by at least about 5 points;keeping insoluble materials in the crankcase of an internal combustion engine | CASTROL LIMITED (GB) | 2011-07-19 | — | — | US | disclosed |
| EP-1513794-A4 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LTD (GB) | 2008-09-10 | — | — | EP | disclosed |
| US-20080139423-A1 | Preparation of Monomers for Grafting to Polyolefins, and Lubricationg Oil Compositions Containing Graft Copolymer | GOLDBLATT IRWIN L | 2008-06-12 | — | — | US | disclosed |
| US-7371713-B2 | Preparation of monomers for grafting to polyolefins, and lubricating oil compositions containing grafted copolymer | CASTROL LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| EP-1513794-A2 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LIMITED (GB) | 2005-03-16 | — | — | EP | disclosed |
| US-20040043909-A1 | Preparation of monomers for grafting to polyolefins, and lubricating oil compositions containing grafted copolymer | CASTROL LIMITED (GB) | 2004-03-04 | — | — | US | disclosed |
| WO-2003099890-A2 | PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER | CASTROL LIMITED (GB) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120323018-A1 | Preparation of Monomers for Grafting to Polyolefins, and Lubricating Oil Compositions Containing Grafted Copolymer | ALOX5, ACMSD, F12 | POLB 639/4885GSK3B 4728/4885ALDH1A1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.