Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.72 |
| ▸ | HTR1A | P08908 | 3/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814536 | 1.00 | SLC6A4 (0.72) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9548998 | 0.94 | HTR1A (0.65) | SLC6A4HTR1A | |
| SCHEMBL8809960 | 0.94 | SLC6A4 (0.69) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8813694 | 0.94 | SLC6A4 (0.69) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8808941 | 0.91 | HTR1A (0.75) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8808946 | 0.91 | HTR1A (0.75) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9326614 | 0.89 | SLC6A4 (0.66) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9326678 | 0.89 | SLC6A4 (0.66) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9549455 | 0.88 | SLC6A4 (0.80) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9326361 | 0.87 | HTR1A (0.68) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288749-A | Treating central nervous system or cardiovascular disorders | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |