⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086432 | 0.63 | GABRP (0.31) | — | |
| Hydrochloric Acid SCHEMBL18320900 | 0.62 | LMNA (0.33) | — | |
| SCHEMBL6674534 | 0.61 | — | — | |
| SCHEMBL906168 | 0.61 | SERPINE1 (0.35) | — | |
| SCHEMBL9165242 | 0.61 | SERPINE1 (0.35) | — | |
| SCHEMBL1070318 | 0.61 | SERPINE1 (0.35) | — | |
| SCHEMBL10618631 | 0.60 | CHRNA7 (0.32) | — | |
| SCHEMBL126557 | 0.60 | SERPINE1 (0.38) | — | |
| SCHEMBL14744313 | 0.60 | CHRNA7 (0.32) | — | |
| SCHEMBL26834 | 0.60 | SERPINE1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243645-B1 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0219782-B1 | USE OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF ATHEROSCLEROSIS, THROMBOSIS AND PERIPHERAL VASCULAR DISEASE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0417473-B1 | TREATMENT OF CARDIAC AND ALSO VASCULAR HYPERTROPHY AND HYPERPLASIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |