Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766058 | 0.85 | ESR1 (0.50) | ESR1ESR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29399630 | 0.85 | ESR1 (0.50) | ESR1ESR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29412586 | 0.85 | ESR1 (0.50) | ESR1ESR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL336470 | 0.82 | SRD5A2 (0.61) | SRD5A2ESR1ESR2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8505603 | 0.80 | SRD5A2 (0.59) | SRD5A2ESR1ESR2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL19837805 | 0.80 | SRD5A2 (0.59) | SRD5A2ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL14030840 | 0.80 | HDAC6 (0.45) | ESR1ESR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4295432 | 0.79 | ALDH1A1 (0.52) | ESR1ESR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9291271 | 0.79 | SRD5A2 (0.48) | SRD5A2ESR1ESR2KDM4EHSD17B10 | |
| SCHEMBL9742570 | 0.79 | ESR1 (0.69) | SRD5A2ESR1ESR2ALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291778-B1 | Process for the preparation of high temperature-resistant dielectrics | SIEMENS AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-4965134-A | Method for manufacturing highly heat-resistant dielectrics | SIEMENS AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| EP-0291778-A1 | Process for the preparation of high temperature-resistant dielectrics | SIEMENS AKTIENGESELLSCHAFT (DE) | 1988-11-23 | — | — | EP | disclosed |