Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MIF | P14174 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327334 | 0.87 | MIF (0.52) | MIFPOLBCYP1A2CYP2C19LMNA | |
| SCHEMBL9325985 | 0.87 | CA1 (0.43) | MIFMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9751158 | 0.71 | MIF (0.56) | MIFKMT2APOLBCYP1A2CYP2C19 | |
| SCHEMBL9751216 | 0.71 | CA1 (0.48) | MEN1KMT2ASMN1; SMN2POLBCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL9751139 | 0.70 | MIF (0.55) | MIFKMT2APOLBCYP1A2CYP2C19 | |
| SCHEMBL8578279 | 0.70 | MAOB (0.51) | MAOBMIFMEN1MAPK10KMT2A | |
| SCHEMBL9327057 | 0.69 | CA1 (0.49) | MIFMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9751313 | 0.69 | MIF (0.47) | MIFMEN1MAPK10KMT2APOLB | |
| SCHEMBL8578277 | 0.68 | MAOB (0.50) | MAOBMIFMEN1MAPK10KMT2A | |
| SCHEMBL14214318 | 0.68 | MAOB (0.50) | MAOBMIFMEN1MAPK10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313997-B1 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |