Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327263 | 0.87 | MAOB (0.42) | MIFPOLBCYP1A2CYP2C19LMNA | |
| SCHEMBL9325985 | 0.86 | CA1 (0.43) | MIFPOLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL9751158 | 0.84 | MIF (0.56) | MIFPOLBCYP1A2CYP2C19CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL9751139 | 0.83 | MIF (0.55) | MIFPOLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL19873011 | 0.74 | MIF (0.57) | MIFPOLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL12294023 | 0.72 | MIF (0.70) | MIFNPC1RAB9A | |
| SCHEMBL3981656 | 0.71 | CYP1A2 (0.68) | MIFPOLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL21066132 | 0.71 | POLB (0.56) | MIFPOLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9751216 | 0.70 | CA1 (0.48) | POLBCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL3981660 | 0.70 | MIF (0.67) | MIFNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313997-B1 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |