Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327057 | 0.87 | CA1 (0.49) | CA1CA2ATMPKMPOLB | |
| SCHEMBL9325985 | 0.84 | CA1 (0.43) | CA1CA2ATMPOLBLMNA | |
| SCHEMBL9326044 | 0.83 | CA1 (0.51) | CA1CA2ATMPKMPOLB | |
| SCHEMBL9751233 | 0.80 | CA1 (0.43) | CA1CA2POLBLMNANPC1 | |
| SCHEMBL27976325 | 0.76 | CA1 (0.50) | CA1CA2ATMPKMPOLB | |
| SCHEMBL6155053 | 0.73 | CA1 (0.50) | CA1CA2ATMPKM | |
| SCHEMBL28653891 | 0.72 | CA1 (0.49) | CA1CA2ATMPKM | |
| SCHEMBL9327263 | 0.71 | MAOB (0.42) | POLBLMNAALDH1A1MEN1CYP1A2 | |
| SCHEMBL17323274 | 0.70 | CA1 (0.68) | CA1CA2POLBAPAF1GRK2 | |
| SCHEMBL9327334 | 0.70 | MIF (0.52) | POLBLMNANPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |