Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582765 | 1.00 | PRCP (0.53) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL15848419 | 0.87 | PRCP (0.68) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL15848417 | 0.87 | PRCP (0.68) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL3343952 | 0.86 | PRCP (0.61) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL6128238 | 0.86 | PRCP (0.70) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL16498829 | 0.85 | PRCP (0.59) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL690268 | 0.84 | HPGDS (0.54) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL690267 | 0.84 | HPGDS (0.54) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL933102 | 0.83 | PRCP (0.52) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL15848588 | 0.83 | PRCP (0.56) | PRCPNR1I2ABCB11CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112100-A1 | Hepatitis C Virus Inhibitors | PFIZER INC. | 2011-05-12 | — | — | US | disclosed |
| WO-2011004276-A1 | HEPATITIS C VIRUS INHIBITORS | PFIZER LIMITED (GB) | 2011-01-13 | — | — | WO | disclosed |
| CN-101534829-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-101528232-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-09-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112100-A1 | Hepatitis C Virus Inhibitors | HAVCR2, SLC10A1, HCCS | PRCP 211/4885NR1I2 245/4885ABCB11 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.