Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751207 | 0.80 | SORT1 (0.43) | SORT1TSHRLAP3MGLL | |
| SCHEMBL9325985 | 0.76 | CA1 (0.43) | LMNATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11982348 | 0.68 | SORT1 (0.45) | SORT1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL24518108 | 0.68 | POLB (0.49) | SORT1LMNATSHRSMN1; SMN2MEN1 | |
| SCHEMBL2919709 | 0.67 | TSHR (0.47) | SORT1TSHR | |
| SCHEMBL24517975 | 0.67 | TSHR (0.43) | SORT1LMNATSHRSMN1; SMN2MEN1 | |
| Diphenylmethane SCHEMBL28636188 | 0.67 | CALM1 (0.55) | LMNATSHRMEN1KMT2ALAP3 | |
| SCHEMBL2920823 | 0.65 | SLC6A2 (0.44) | SORT1 | |
| SCHEMBL7799021 | 0.63 | SORT1 (0.40) | SORT1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7789573 | 0.62 | SORT1 (0.39) | SORT1SMN1; SMN2TDP1L3MBTL1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313997-B1 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |