Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 4/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679686 | 0.86 | FABP3 (0.36) | KDM4EL3MBTL1ALDH1A1FABP3FABP4 | |
| SCHEMBL9700766 | 0.81 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL8547768 | 0.81 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL14240074 | 0.81 | EGLN1 (0.45) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL26204900 | 0.81 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1FABP3FABP4 | |
| SCHEMBL24510627 | 0.81 | FABP3 (0.40) | KDM4EALDH1A1MAPTFABP3FABP4 | |
| SCHEMBL8545718 | 0.81 | KDM4E (0.37) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL18289562 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTFABP3FABP4 | |
| SCHEMBL26726844 | 0.77 | POLB (0.40) | KDM4EL3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL17667393 | 0.76 | KDM6B (0.33) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288866-A | Chemical intermediates in the preparation of purity herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0161221-B1 | PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4748244-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0161221-A2 | Process for the preparation of pyridine-2,3-dicarboxylic-acid derivatives and of 1-amino-1,4-dihydropyridine-2,3-dicarboxylic-acid derivatives | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |