Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327394 | 0.89 | KMT2A (0.53) | KMT2APPARGPPARACA1CA2 | |
| SCHEMBL9329257 | 0.89 | TP53 (0.55) | KMT2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL7999041 | 0.88 | PPARG (0.50) | KMT2APPARGPPARATAS1R3TAS1R1 | |
| SCHEMBL2230124 | 0.86 | PPARG (0.63) | KMT2APPARGPPARACA1CA2 | |
| SCHEMBL7335069 | 0.86 | PPARG (0.55) | KMT2APPARGPPARATSHR | |
| SCHEMBL28686243 | 0.81 | KMT2A (0.47) | KMT2APPARGPPARACA1CA2 | |
| SCHEMBL9327404 | 0.81 | HTT (0.46) | KMT2APPARGPPARATP53TSHR | |
| SCHEMBL5162436 | 0.79 | RAB9A (0.51) | KMT2ACA1CA2MAPK1TSHR | |
| SCHEMBL13572608 | 0.79 | ELANE (0.47) | PPARGPPARAHTT | |
| SCHEMBL1952125 | 0.79 | KMT2A (0.59) | KMT2ACA1CA2MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368912-B1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INST TECHNOLOGY (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0368912-A4 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | — | 1990-12-19 | — | — | EP | disclosed |
| EP-0368912-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4857311-A | FROM P-CARBOXYPHEN(-OXY OR -YL)ALKANOIC ACID; BIODEGRADABLE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-08-15 | — | — | US | disclosed |
| WO-1989000855-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-02-09 | — | — | WO | disclosed |