SCHEMBL28686243

SCHEMBL28686243

CCOC(=O)CC(Oc1ccc(C(=O)O)cc1)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HTT P42858 1/20 0.43
PLA2G4B P0C869 2/20 0.42
MAPK1 P28482 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
RAB9A P51151 2/20 0.38
SRD5A2 P31213 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
GAA P10253 1/20 0.38
PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327414 0.81 KMT2A (0.51) KMT2ACA1CA2HTTPLA2G4B
SCHEMBL9329257 0.77 TP53 (0.55) KMT2AHTTPLA2G4BTP53TSHR
SCHEMBL27533809 0.76 AR (0.37) KMT2ATSHRMAPTALDH1A1SMN1; SMN2
SCHEMBL2339923 0.73 LMNA (0.62) KMT2ACA1CA2HTTPLA2G4B
SCHEMBL1963387 0.73 LMNA (0.62) KMT2ACA1CA2HTTPLA2G4B
SCHEMBL5671174 0.72 ALDH1A1 (0.47) KMT2AMAPK1TSHRALDH1A1NPC1
SCHEMBL28570983 0.72 KMT2A (0.65) KMT2ACA1CA2MAPK1MAPT
SCHEMBL28570985 0.72 KMT2A (0.65) KMT2ACA1CA2MAPK1MAPT
SCHEMBL2231218 0.72 SMN1; SMN2 (0.63) KMT2ACA1CA2HTTPLA2G4B
SCHEMBL27939672 0.72 KMT2A (0.65) KMT2ACA1CA2MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968785-B Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-09-30 CN claimed
CN-113968785-A Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-01-25 CN claimed
CN-113968785-B Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-09-30 CN disclosed
CN-113968785-B Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-09-30 CN disclosed
CN-113968785-A Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-01-25 CN disclosed
CN-113968785-A Oxygen-containing benzoic acid in purslane and extraction and separation method and application thereof 辽宁中医药大学 2022-01-25 CN disclosed