Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20067022 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL20067055 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL20067031 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL20067023 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL28436234 | 0.96 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL2610373 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL9329713 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| 1,4-Butanediol SCHEMBL15422850 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Ethylene Glycol SCHEMBL10531251 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL7696055 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856188-B1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| US-20220112184-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC | 2022-04-14 | — | — | US | disclosed |
| US-11130752-B2 | Aminopyrimidine compound | CARDURION PHARMACEUTICALS, LLC (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200095240-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC | 2020-03-26 | — | — | US | disclosed |
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | disclosed |
| EP-0381974-B1 | Thiophene azo dyes with a coupling component based on m-phenylene diamine | BASF AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5145952-A | Blue, textiles | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0381974-A2 | Thiophene azo dyes with a coupling component based on m-phenylene diamine | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130752-B2 | Aminopyrimidine compound | CALM1, CAMK4, CAMK2B | ALDH1A1 1145/4885TSHR 2471/4885CHRM5 842/4885 |
| US-20200095240-A1 | AMINOPYRIMIDINE COMPOUND | CALM1, CAMK4, CAMK2B | ALDH1A1 1145/4885TSHR 2471/4885CHRM5 842/4885 |
| US-20220112184-A1 | AMINOPYRIMIDINE COMPOUND | CALM1, CAMK4, CAMK2B | ALDH1A1 1145/4885TSHR 2471/4885CHRM5 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.