Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933479 | 0.85 | BACE1 (0.34) | BACE1 | |
| SCHEMBL932026 | 0.85 | BACE1 (0.34) | BACE1 | |
| SCHEMBL932334 | 0.80 | HCRTR1 (0.37) | BACE1AAK1 | |
| SCHEMBL933050 | 0.80 | HCRTR1 (0.37) | BACE1AAK1 | |
| SCHEMBL967621 | 0.79 | BACE1 (0.34) | BACE1AAK1 | |
| SCHEMBL933488 | 0.77 | HCRTR1 (0.37) | AAK1 | |
| SCHEMBL1421185 | 0.75 | AAK1 (0.35) | BACE1AAK1 | |
| SCHEMBL933007 | 0.71 | BACE1 (0.53) | BACE1 | |
| SCHEMBL14961814 | 0.70 | BACE1 (0.44) | BACE1AAK1 | |
| SCHEMBL932583 | 0.70 | BACE1 (0.44) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451793-A1 | BACE INHIBITORS | Eli Lilly and Company (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005738-A1 | BACE INHIBITORS | ELI LILLY AND COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |