Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327839 | 0.85 | STAT3 (0.43) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL27987824 | 0.83 | STAT3 (0.42) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL7971294 | 0.83 | ESR1 (0.51) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL662974 | 0.81 | CES2 (0.50) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL4203797 | 0.81 | MAPT (0.48) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL30208125 | 0.81 | MAPT (0.48) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL7058435 | 0.80 | CA12 (0.47) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL10228048 | 0.79 | ESR1 (0.36) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL25977558 | 0.79 | STAT3 (0.42) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL9330766 | 0.79 | CA12 (0.52) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296479-B1 | Fluorobenzoates and process for their production | IHARA CHEMICAL IND CO (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-4916253-A | Fluorobenzoates and process for their production | IHARA CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0296479-A2 | Fluorobenzoates and process for their production | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1988-12-28 | — | — | EP | disclosed |