Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 4/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011629 | 0.91 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Sulfuric Acid SCHEMBL9257038 | 0.83 | — | — | |
| SCHEMBL31333159 | 0.79 | GRIK1 (0.42) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Aspartic Acid SCHEMBL8888026 | 0.78 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Aspartic Acid SCHEMBL8888023 | 0.78 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL27779438 | 0.77 | GRIK1 (0.43) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Aspartic Acid SCHEMBL28252064 | 0.74 | GRIK1 (0.45) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL25491149 | 0.73 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL14882533 | 0.73 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL19107032 | 0.73 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294362-A | Bleach | AUSIMONT S.R.L. (IT) | 1994-03-15 | — | — | US | disclosed |
| US-5245075-A | Bleaching agents | AUSIMONT S.R.L. (IT) | 1993-09-14 | — | — | US | disclosed |