Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328172 | 0.85 | CYP1A2 (0.35) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9356115 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9127086 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9329816 | 0.77 | HSPA5 (0.51) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9328465 | 0.75 | TYR (0.40) | ALDH1A1TYRHIF1A | |
| SCHEMBL9330473 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL225440 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29463589 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL3421497 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL8390711 | 0.72 | CYP1A2 (0.36) | CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357048-B1 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0358985-B1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0312790-B1 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5136075-A | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5061818-A | Fluorination with metal or ammonium fluoride in presence of pyridine halide salt | ETHYL CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-5049691-A | Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride | ETHYL CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929745-A | Transhalogenation of halophosphorus compounds | EHTYL CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4910324-A | Using a metal or ammonium fluoride | ETHYL CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |