Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187988 | 0.85 | CYP1A2 (0.35) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9328276 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9356071 | 0.81 | HSPA5 (0.38) | HSPA5 | |
| SCHEMBL9516260 | 0.81 | TACR1 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9515212 | 0.81 | CRHR1 (0.30) | — | |
| SCHEMBL1406187 | 0.80 | CYP3A4 (0.43) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9355815 | 0.79 | RORC (0.30) | — | |
| SCHEMBL9356369 | 0.77 | HSPA5 (0.51) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9356422 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29463589 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | claimed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | claimed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | claimed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |