Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446441 | 0.84 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL9356123 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL9328182 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TYRCYP2C19MAPT | |
| SCHEMBL10442446 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL9328476 | 0.74 | TYR (0.36) | TYRPTGS1HTTMAPT | |
| SCHEMBL17594923 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL9330485 | 0.71 | MRGPRX4 (0.36) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL9329822 | 0.71 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL8390717 | 0.69 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1CA2TYRPTGS2 | |
| SCHEMBL10442447 | 0.69 | USP2 (0.36) | SMN1; SMN2ALDH1A1POLBCA2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357048-B1 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0358985-B1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0312790-B1 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5136075-A | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5061818-A | Fluorination with metal or ammonium fluoride in presence of pyridine halide salt | ETHYL CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-5049691-A | Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride | ETHYL CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929745-A | Transhalogenation of halophosphorus compounds | EHTYL CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4910324-A | Using a metal or ammonium fluoride | ETHYL CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |