Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905507 | 0.92 | CYP2C19 (0.46) | GABRR1CYP1A2FOLH1NAALAD2BLM | |
| SCHEMBL18052197 | 0.86 | GABRR1 (0.54) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL1177351 | 0.86 | GABRR1 (0.54) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL9736766 | 0.86 | TDP1 (0.45) | GABRR1CYP1A2TP53FOLH1NAALAD2 | |
| SCHEMBL27597486 | 0.85 | GABRR1 (0.38) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL1413247 | 0.84 | CPA1 (0.41) | GABRR1CYP1A2TP53FOLH1NAALAD2 | |
| SCHEMBL6469043 | 0.84 | ENPEP (0.45) | GABRR1CYP1A2TP53FOLH1NAALAD2 | |
| Hydrochloric Acid SCHEMBL28487836 | 0.84 | GABRR1 (0.52) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL4812171 | 0.84 | GABRR1 (0.41) | GABRR1CYP1A2TP53FOLH1NAALAD2 | |
| SCHEMBL10411823 | 0.83 | ESRRB (0.41) | GABRR1CYP1A2FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359340-B1 | Spirodilactam polymers | SHELL INT RESEARCH (NL) | 1994-03-16 | — | — | EP | disclosed |
| EP-0359341-B1 | 1,6-diazaspiro[4,4]nonane-2,7-dione derivatives | SHELL INT RESEARCH (NL) | 1994-02-16 | — | — | EP | disclosed |
| EP-0336475-B1 | 1,6-DIAZASPIRO (4,4)NONANE-2,7-DIONE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-12-23 | — | — | EP | disclosed |
| US-5164470-A | Polymer compositions | SHELL OIL COMPANY (US) | 1992-11-17 | — | — | US | disclosed |
| US-5103001-A | SPIRODILACTAMS | SHELL OIL COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5093495-A | Benzoheterocyclic compounds | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5093465-A | Polyamide containing spirodilactam moieties | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5093500-A | Spirodilactam bisimides | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5071996-A | Benzheterocyclic compounds | SHELL OIL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| US-5034504-A | Spirodilactam polyamide polymer | SHELL OIL COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-4968770-A | Polyamide from spirodilactam precursor and primary diamine | SHELL OIL COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4940801-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4939251-A | Novel spirolactones | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4939270-A | Spirodilactam diamines | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4927906-A | Novel polyamideimide polymers | SHELL OIL COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0359341-A2 | 1,6-diazaspiro[4,4]nonane-2,7-dione derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| EP-0359340-A2 | Spirodilactam polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| US-4908458-A | 1,5-Di(benzoheterocyclic)-3-oxopentane derivatives | SHELL OIL COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| US-4885351-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0336475-A1 | 1,6-diazaspiro (4,4)nonane-2,7-dione derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-11 | — | — | EP | disclosed |