SCHEMBL9328562

SCHEMBL9328562

O=C(O)c1ccccc1N1C(=O)c2cccc(C(=O)O)c2C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.56
ALDH1A1 P00352 6/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
GAA P10253 2/20 0.47
TYMS P04818 2/20 0.46
POLB P06746 2/20 0.46
KDM4E B2RXH2 1/20 0.46
APOBEC3A P31941 1/20 0.46
RECQL P46063 1/20 0.46
CASP6 P55212 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALOX15 P16050 1/20 0.45
HSPA1A P0DMV8 1/20 0.45
PABPC1 P11940 1/20 0.45
HNF4A P41235 1/20 0.45
PIM3 Q86V86 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327586 0.89 CTDSP1 (0.53) APEX1CTDSP1ALDH1A1L3MBTL1LMNA
N-Phthaloylanthranilic Acid SCHEMBL481284 0.88 APEX1 (0.71) APEX1ALDH1A1L3MBTL1LMNAMAPT
N-Phthaloylanthranilic Acid SCHEMBL29549628 0.88 APEX1 (0.71) APEX1ALDH1A1L3MBTL1LMNAMAPT
SCHEMBL9405313 0.85 CTDSP1 (0.65) APEX1CTDSP1ALDH1A1L3MBTL1LMNA
SCHEMBL4234504 0.83 LMNA (0.67) APEX1L3MBTL1LMNAPOLBKDM4E
SCHEMBL22717018 0.83 MEN1 (0.60) APEX1ALDH1A1L3MBTL1MAPTGAA
SCHEMBL28480758 0.81 MAPT (0.50) APEX1CTDSP1ALDH1A1L3MBTL1LMNA
SCHEMBL11845327 0.81 CTDSP1 (0.67) APEX1CTDSP1ALDH1A1L3MBTL1LMNA
SCHEMBL27873776 0.79 APEX1 (0.56) APEX1CTDSP1ALDH1A1L3MBTL1LMNA
SCHEMBL481455 0.79 NR1H2 (0.59) APEX1ALDH1A1L3MBTL1GAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375960-B1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO (JP) 1994-03-30 EP claimed
US-5120820-A Injection molding materials having dimensional stability and accuracy; fluid flow; electronic and automobile parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-09 US claimed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP claimed
JP-2147631-A None JP disclosed
EP-0375960-B1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO (JP) 1994-03-30 EP disclosed
US-5120820-A Injection molding materials having dimensional stability and accuracy; fluid flow; electronic and automobile parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-09 US disclosed
US-5120820-A Injection molding materials having dimensional stability and accuracy; fluid flow; electronic and automobile parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-09 US disclosed
US-5109100-A Polyeserimide copolymer; dimensional stability IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-04-28 US disclosed
US-5109100-A Polyeserimide copolymer; dimensional stability IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-04-28 US disclosed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP disclosed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP disclosed
JP-H02147631-A THERMOPLASTIC, LIQUID-CRYSTAL WHOLLY, AROMATIC POLYIMIDE ESTER AND PREPARATION THEREOF IDEMITSU PETROCHEM CO LTD 1990-06-06 JP disclosed