SCHEMBL481455

SCHEMBL481455

O=C(O)c1ccccc1N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 10/20 0.59
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA9 Q16790 1/20 0.53
APEX1 P27695 1/20 0.52
NR1H3 Q13133 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 1/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MYC P01106 1/20 0.45
NR4A1 P22736 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18066940 0.89 NR1H2 (0.49) NR1H2CA2CA7CA12CA1
SCHEMBL11646227 0.84 APEX1 (0.56) APEX1ALDH1A1ALOX15GAAL3MBTL1
SCHEMBL7560762 0.82 NR1H2 (0.70) NR1H2CA2CA7CA1NR1H3
N-Phthaloylanthranilic Acid SCHEMBL481284 0.79 APEX1 (0.71) NR1H2CA2CA12CA1CA9
N-Phthaloylanthranilic Acid SCHEMBL29549628 0.79 APEX1 (0.71) NR1H2CA2CA12CA1CA9
SCHEMBL9328562 0.79 APEX1 (0.58) NR1H2APEX1ALDH1A1ALOX15GAA
SCHEMBL8889877 0.77 MYC (0.58) APEX1ALDH1A1ALOX15GAAL3MBTL1
Hydrochloric Acid SCHEMBL7461209 0.76 MYC (0.56) APEX1ALDH1A1ALOX15GAAL3MBTL1
SCHEMBL9686180 0.73 APEX1 (0.52) CA2CA7CA12CA1CA9
SCHEMBL183052 0.73 ALDH1A1 (0.71) APEX1ALDH1A1ALOX15GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-2411437-B9 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-07-31 EP disclosed
EP-2411437-B1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-05-08 EP disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-20120029104-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2012-02-02 US disclosed
EP-2411437-A2 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-Chemie GmbH (DE) 2012-02-01 EP disclosed
WO-2010108672-A2 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2010-09-30 WO disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed
US-20060160940-A1 Process for intercalating natural or szynthetic clays with block or comb copolymers CIBA SPECIALTY CHEMICALS CORP. 2006-07-20 US disclosed
US-6849679-B2 Pigment compositions with modified block copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-02-01 US disclosed