Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Syringaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Syringaldehyde SCHEMBL28592447 | 0.85 | ALDH1A1 (0.54) | PKMERN1ALDH1A1MEN1KMT2A | |
| Syringaldehyde SCHEMBL31412823 | 0.85 | PKM (0.62) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL30119623 | 0.83 | ALDH1A1 (0.62) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL150376 | 0.83 | ALDH1A1 (0.62) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL2110596 | 0.83 | ALDH1A1 (0.62) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL29268875 | 0.81 | CYP3A4 (0.59) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL29724072 | 0.81 | ALDH1A1 (0.60) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL28642631 | 0.81 | ALDH1A1 (0.60) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL11013780 | 0.81 | ALDH1A1 (0.60) | PKMCA12CA1CA2CA3 | |
| Syringaldehyde SCHEMBL27352107 | 0.81 | ALDH1A1 (0.60) | PKMCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375723-B1 | SUBSTRATES FOR THE ASSAY OF ENZYMES | KING S COLLEGE LONDON (GB) | 1994-03-23 | — | — | EP | disclosed |
| US-5221606-A | REAGENT AND KIT FOR ENZYME ASSAY COMPRISING A SUBSTRATE CONSONANT WITH GIVEN ENZYME TO BE ASSAYED | KING'S COLLEGE LONDON (GB) | 1993-06-22 | — | — | US | disclosed |
| EP-0375723-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES. | KING S COLLEGE LONDON (GB) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989002473-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES | KING'S COLLEGE LONDON (GB) | 1989-03-23 | — | — | WO | disclosed |