SCHEMBL9328690

SCHEMBL9328690

Nc1ccc(S(=O)(=O)c2ccc(C(=O)O)cc2)cc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.55
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
CA9 Q16790 5/20 0.55
CA14 Q9ULX7 4/20 0.55
CA3 P07451 2/20 0.55
CA6 P23280 2/20 0.55
CA5A P35218 2/20 0.55
CA7 P43166 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
CYP2C19 P33261 1/20 0.55
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
CDC25B P30305 1/20 0.53
APEX1 P27695 3/20 0.50
POLB P06746 2/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 3/20 0.49
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473321 0.86 GAA (0.69) CA12CA1CA2CA9CA14
SCHEMBL29400283 0.86 GAA (0.69) CA12CA1CA2CA9CA14
SCHEMBL1732418 0.86 GAA (0.69) CA12CA1CA2CA9CA14
SCHEMBL273153 0.86 GAA (0.69) CA12CA1CA2CA9CA14
SCHEMBL564602 0.84 GAA (0.58) CA12CA1CA2CA9CA14
SCHEMBL564630 0.82 GAA (0.60) CA12CA1CA2CA9CA7
SCHEMBL564590 0.82 HTR6 (0.69) CA12CA1CA2CA9CA14
SCHEMBL2917437 0.80 CA1 (0.67) CA12CA1CA2CA9CA14
SCHEMBL22349 0.80 CA1 (0.67) CA12CA1CA2CA9CA14
SCHEMBL5581302 0.80 CA1 (0.67) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291778-B1 Process for the preparation of high temperature-resistant dielectrics SIEMENS AG (DE) 1994-03-16 EP disclosed
US-4965134-A Method for manufacturing highly heat-resistant dielectrics SIEMENS AKTIENGESELLSCHAFT (DE) 1990-10-23 US disclosed
EP-0291778-A1 Process for the preparation of high temperature-resistant dielectrics SIEMENS AKTIENGESELLSCHAFT (DE) 1988-11-23 EP disclosed