Sugi Predict

Sugi Predict / Compounds / SCHEMBL564590

SCHEMBL564590

SCHEMBL564590

Nc1ccc(S(=O)(=O)c2ccc(N)c(O)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 3/20 0.69
▸ ALDH1A1 P00352 3/20 0.69
▸ PKM P14618 3/20 0.69
▸ TSHR P16473 3/20 0.61
▸ LMNA P02545 2/20 0.61
▸ CYP3A4 P08684 2/20 0.61
▸ MPO P05164 1/20 0.61
▸ CYP2C9 P11712 1/20 0.61
▸ GAA P10253 2/20 0.60
▸ MAPT P10636 2/20 0.60
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ NPC1 O15118 1/20 0.51
▸ HKDC1 Q2TB90 1/20 0.49
▸ HSD17B10 Q99714 2/20 0.48
▸ CA1 P00915 4/20 0.48
▸ CA2 P00918 4/20 0.48
▸ CA12 O43570 3/20 0.48
▸ CA9 Q16790 3/20 0.48
▸ CA14 Q9ULX7 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273153 0.92 GAA (0.69) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL30473321 0.92 GAA (0.69) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL1732418 0.92 GAA (0.69) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL29400283 0.92 GAA (0.69) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL564630 0.89 GAA (0.60) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL564602 0.87 GAA (0.58) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL10541393 0.85 GAA (0.57) HTR6ALDH1A1PKMGAAMAPT
SCHEMBL565259 0.85 GAA (0.85) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL6853711 0.85 GAA (0.85) HTR6ALDH1A1PKMTSHRLMNA
SCHEMBL564760 0.84 LMNA (0.69) HTR6ALDH1A1PKMTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed
EP-0431971-B1 Photosensitive composition and resin-encapsulated semiconductor device TOSHIBA KK (JP) 1995-07-19 — — EP disclosed
EP-0431971-A2 Photosensitive composition and resin-encapsulated semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1991-06-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 HTR6 850/4885ALDH1A1 204/4885PKM 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.