Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23595821 | 0.79 | CYP11B2 (0.54) | KMT2AMAPTCYP11B2 | |
| SCHEMBL3438226 | 0.79 | CYP11B2 (0.54) | KMT2AMAPTCYP11B2 | |
| SCHEMBL9330239 | 0.78 | TLR4 (0.37) | TLR4CA1CA2CA4KMT2A | |
| SCHEMBL9329125 | 0.78 | CYP11B2 (0.57) | KMT2AMAPTCYP11B2 | |
| SCHEMBL3438253 | 0.77 | DDB1 (0.50) | TLR4CA1CA2CA4KMT2A | |
| SCHEMBL10743801 | 0.75 | KDM4E (0.39) | — | |
| Ethylene SCHEMBL27706119 | 0.74 | DDB1 (0.47) | TLR4CA1CA2CA4KMT2A | |
| SCHEMBL9328081 | 0.73 | CYP11B2 (0.51) | KMT2AMAPTCYP11B2 | |
| SCHEMBL15874652 | 0.72 | SLC18A3 (0.51) | TLR4CA1MCL1SLC18A3MAPT | |
| SCHEMBL190786 | 0.72 | SLC18A3 (0.51) | TLR4CA1MCL1SLC18A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| US-5151436-A | Compounds for inhibiting hair loss in men | RHONE-POULENC SANTE (FR) | 1992-09-29 | — | — | US | disclosed |
| EP-0321274-A1 | Derivatives of thioformamide | RHONE POULENC RORER LIMITED (GB) | 1989-06-21 | — | — | EP | disclosed |