Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328826 | 0.78 | TLR4 (0.42) | TLR4KMT2ACA1CA2CA4 | |
| SCHEMBL28412030 | 0.75 | POLB (0.47) | TLR4ALDH1A1LMNANPC1L3MBTL1 | |
| SCHEMBL19993834 | 0.74 | LMNA (0.42) | TLR4LMNANPC1MEN1KMT2A | |
| SCHEMBL31014511 | 0.73 | CYP11B2 (0.46) | TAS1R3TAS1R1TAS1R2ALDH1A1LMNA | |
| SCHEMBL23595821 | 0.72 | CYP11B2 (0.54) | ALDH1A1LMNASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL3438226 | 0.72 | CYP11B2 (0.54) | ALDH1A1LMNASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL4128802 | 0.72 | ATM (0.46) | ALDH1A1LMNASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL9329125 | 0.71 | CYP11B2 (0.57) | ALDH1A1LMNASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL16196252 | 0.71 | CYP11B2 (0.44) | TAS1R3TAS1R1TAS1R2ALDH1A1LMNA | |
| SCHEMBL3438253 | 0.70 | DDB1 (0.50) | TLR4ALDH1A1SMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| US-5151436-A | Compounds for inhibiting hair loss in men | RHONE-POULENC SANTE (FR) | 1992-09-29 | — | — | US | disclosed |
| EP-0321274-A1 | Derivatives of thioformamide | RHONE POULENC RORER LIMITED (GB) | 1989-06-21 | — | — | EP | disclosed |