Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159834 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL6159837 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL9330267 | 0.80 | CYP1A2 (0.50) | ALDH1A1MAPTMEN1CYP1A2HPGD | |
| SCHEMBL9330263 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL27852162 | 0.78 | MAPT (0.49) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL15888226 | 0.75 | BACE1 (0.59) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL9756691 | 0.74 | CA12 (0.47) | ALDH1A1MAPTKDM4EMEN1ALOX15 | |
| SCHEMBL4678281 | 0.74 | TTR (0.47) | ALDH1A1MAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL4678277 | 0.74 | TTR (0.47) | ALDH1A1MAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL9756693 | 0.74 | CA12 (0.47) | ALDH1A1MAPTKDM4EMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300387-B1 | Phenyl alkenylcarboxylic acids and their esters | BASF AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| US-5123955-A | Herbicides, chloro and tetrahydrophthalimido-substituted phenyl | PLATH PETER (DE) | 1992-06-23 | — | — | US | disclosed |
| US-4933001-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |