Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888012 | 0.84 | ELANE (0.71) | ELANE | |
| SCHEMBL18566937 | 0.83 | ELANE (0.69) | ELANE | |
| SCHEMBL10483720 | 0.82 | ELANE (1.00) | ELANEKMT2A | |
| SCHEMBL22369614 | 0.81 | ELANE (0.86) | ELANE | |
| SCHEMBL3657615 | 0.80 | ELANE (0.76) | ELANEKMT2A | |
| SCHEMBL16189796 | 0.80 | ELANE (0.76) | ELANEALDH1A1 | |
| SCHEMBL12569396 | 0.80 | TAAR1 (0.57) | ELANETAAR1MAOBKDM4EALDH1A1 | |
| SCHEMBL3657617 | 0.80 | ELANE (0.76) | ELANE | |
| SCHEMBL23836711 | 0.80 | ELANE (0.65) | ELANE | |
| SCHEMBL29264689 | 0.80 | TAAR1 (0.55) | TAAR1MAOBKDM4EALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649451-B2 | Evolution of bioactive sequence-defined synthetic polymers using DNA-templated polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-05-16 | — | — | US | disclosed |
| US-11649451-B2 | Evolution of bioactive sequence-defined synthetic polymers using DNA-templated polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-05-16 | — | — | US | disclosed |
| US-20200172896-A1 | EVOLUTION OF BIOACTIVE SEQUENCE-DEFINED SYNTHETIC POLYMERS USING DNA-TEMPLATED POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2019010441-A1 | EVOLUTION BIOACTIVE SEQUENCE-DEFINED SYNTHETIC POLYMERS USING DNA-TEMPLATED POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172896-A1 | EVOLUTION OF BIOACTIVE SEQUENCE-DEFINED SYNTHETIC POLYMERS USING DNA-TEMPLATED POLYMERIZATION | PCSK9, IL6, PCSK6 | ELANE 972/4885TAAR1 4263/4885MAOB 2973/4885 |
| US-11649451-B2 | Evolution of bioactive sequence-defined synthetic polymers using DNA-templated polymerization | PCSK9, IL6, PCSK6 | ELANE 972/4885TAAR1 4263/4885MAOB 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.