SCHEMBL29264689

SCHEMBL29264689

NCCc1ccc(OC(=O)Oc2ccc(CCN)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 7/20 0.55
MAOB P27338 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR3A P46098 1/20 0.50
BACE1 P56817 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
HTR2A P28223 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29264776 0.98 TAAR1 (0.53) TAAR1MAOBKDM4EALDH1A1HTR1A
SCHEMBL29264690 0.86 TAAR1 (0.53) TAAR1MAOBKDM4EALDH1A1HTR1A
Hydrochloric Acid SCHEMBL29264777 0.84 TAAR1 (0.52) TAAR1MAOBKDM4EALDH1A1HTR1A
SCHEMBL12569396 0.84 TAAR1 (0.57) TAAR1MAOBKDM4EALDH1A1HTR1A
SCHEMBL18274704 0.84 TAAR1 (0.52) TAAR1MAOBKDM4EALDH1A1HTR1A
SCHEMBL608099 0.83 THRB (0.44) KMT2A
SCHEMBL10336423 0.82 TAAR1 (0.46) TAAR1MAOBKMT2ACYP1A2CYP2A6
SCHEMBL344079 0.81 THRB (0.70) TAAR1MAOBKDM4EALDH1A1HTR1A
SCHEMBL29046738 0.81 PPARA (0.53) KMT2ATDP1
SCHEMBL3059076 0.80 ACHE (0.68) TAAR1MAOBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019750-A Drug delivery system for local delivery of therapeutic agents and uses thereof 上海椿安生物医药科技有限公司 2024-05-10 CN disclosed