Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219191 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9219188 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9398875 | 0.82 | MAPT (0.41) | CHRM2CHRM1OPRM1SLC6A9MAPT | |
| SCHEMBL5349503 | 0.82 | MAPT (0.43) | CHRM2CHRM1CNR2OPRM1MAPT | |
| SCHEMBL9329061 | 0.77 | MAPT (0.40) | CHRM2CHRM1OPRM1ALDH1A1MAPT | |
| SCHEMBL9517542 | 0.76 | ALDH1A1 (0.36) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9517554 | 0.76 | ALDH1A1 (0.36) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL5206248 | 0.75 | SLC22A1 (0.60) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL5205111 | 0.75 | SLC6A4 (0.64) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL4859953 | 0.74 | SLC6A4 (0.62) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| US-5151436-A | Compounds for inhibiting hair loss in men | RHONE-POULENC SANTE (FR) | 1992-09-29 | — | — | US | disclosed |