Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842579 | 0.86 | CNR2 (0.40) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL9398875 | 0.84 | MAPT (0.41) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL28740691 | 0.83 | SLC6A2 (0.41) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL9328997 | 0.82 | CHRM2 (0.47) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL9219188 | 0.82 | CHRM2 (0.47) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL9219191 | 0.82 | CHRM2 (0.47) | MAPTSLC6A2SLC6A4OPRM1SLC22A1 | |
| SCHEMBL588342 | 0.81 | CNR2 (0.41) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL11465118 | 0.77 | MAPT (0.54) | MAPTSLC6A2SLC6A4OPRM1OPRD1 | |
| SCHEMBL9618282 | 0.77 | SLC6A9 (0.41) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL9329144 | 0.77 | CNR1 (0.42) | MAPTMEN1KMT2ACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |