Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329091 | 1.00 | SLC6A3 (0.43) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9330228 | 1.00 | SLC6A3 (0.43) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9329087 | 1.00 | SLC6A3 (0.43) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9330230 | 1.00 | SLC6A3 (0.43) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9370112 | 0.86 | ALDH1A1 (0.37) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9370119 | 0.86 | ALDH1A1 (0.37) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9370116 | 0.86 | ALDH1A1 (0.37) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9425045 | 0.85 | ALDH1A1 (0.36) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9517554 | 0.84 | ALDH1A1 (0.36) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 | |
| SCHEMBL9517542 | 0.84 | ALDH1A1 (0.36) | SLC6A3ALDH1A1SLC6A4CYP11B2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | claimed |
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |