SCHEMBL9329102

SCHEMBL9329102

CC(C)C[C@@H](C(=O)O)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.52
MMP3 P08254 3/20 0.52
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
MMP7 P09237 1/20 0.50
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.45
NR4A2 P43354 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MMP13 P45452 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
ANPEP P15144 1/20 0.43
RNPEP Q9H4A4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15650705 0.87 MMP1 (0.50) MMP1MMP3MMP2MMP9MMP8
SCHEMBL15650703 0.87 MMP1 (0.50) MMP1MMP3MMP2MMP9MMP8
SCHEMBL3463312 0.85 MMP1 (0.44) MMP1MMP3MMP2MMP9MMP8
SCHEMBL28777927 0.85 LMNA (0.46) MMP1MMP3MEN1KMT2ALMNA
SCHEMBL7372235 0.85 NR4A2 (0.55) MMP1MMP3MMP2MMP9MMP8
SCHEMBL3039559 0.85 NR4A2 (0.55) MMP1MMP3MMP2MMP9MMP8
SCHEMBL55669 0.84 EPOR (0.52) MMP1MMP3MMP2MMP9MMP8
SCHEMBL56847 0.84 EPOR (0.52) MMP1MMP3MMP2MMP9MMP8
SCHEMBL55668 0.84 EPOR (0.52) MMP1MMP3MMP2MMP9MMP8
Hydrochloric Acid SCHEMBL3046435 0.83 NR4A2 (0.54) MMP1MMP3MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387605-B1 Process for the stereoselective preparation of optically active S,S or R,R-beta-aminoalcohols BAYER AG (DE) 1994-03-30 EP disclosed