Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.65 |
| ▸ | RARB | P10826 | 4/20 | 0.61 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089107 | 1.00 | TSHR (0.67) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL4209773 | 1.00 | TSHR (0.67) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL4211416 | 0.98 | TSHR (0.64) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL4275826 | 0.90 | HDAC1 (0.56) | TSHRHTTGAAHSD17B10 | |
| SCHEMBL28706802 | 0.88 | GAA (0.75) | TSHRTP53HTTPLA2G4BGAA | |
| SCHEMBL28693964 | 0.88 | GAA (0.75) | TSHRTP53HTTPLA2G4BGAA | |
| SCHEMBL28706034 | 0.88 | GAA (0.75) | TSHRTP53HTTPLA2G4BGAA | |
| SCHEMBL4262672 | 0.88 | MAPT (0.70) | TSHRTP53HTTTDP1GAA | |
| SCHEMBL2603390 | 0.86 | L3MBTL1 (0.74) | HTTPOLBGAA | |
| SCHEMBL5187570 | 0.86 | MAPT (0.72) | HTTTDP1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368912-B1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INST TECHNOLOGY (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0368912-A4 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | — | 1990-12-19 | — | — | EP | disclosed |
| EP-0368912-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4857311-A | FROM P-CARBOXYPHEN(-OXY OR -YL)ALKANOIC ACID; BIODEGRADABLE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-08-15 | — | — | US | disclosed |
| WO-1989000855-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-02-09 | — | — | WO | disclosed |