Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693964 | 0.98 | GAA (0.75) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL28706802 | 0.98 | GAA (0.75) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL28706034 | 0.98 | GAA (0.75) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL11456703 | 0.95 | L3MBTL1 (0.71) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL14385137 | 0.90 | L3MBTL1 (0.68) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL4275826 | 0.88 | HDAC1 (0.56) | L3MBTL1GAAMAPTALDH1A1LMNA | |
| SCHEMBL4211416 | 0.87 | TSHR (0.64) | L3MBTL1POLBHTT | |
| SCHEMBL5187570 | 0.87 | MAPT (0.72) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18868405 | 0.86 | L3MBTL1 (1.00) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL9112440 | 0.86 | L3MBTL1 (0.53) | L3MBTL1GAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075187-B | Carbonyl pyrazole antitumor compound as well as preparation method and application thereof | 山东大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114075187-A | Carbonyl pyrazole anti-tumor compound and preparation method and application thereof | 山东大学 | 2022-02-22 | — | — | CN | disclosed |
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160355682-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20150050685-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2015-02-19 | — | — | US | disclosed |
| US-8822695-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-17 | — | — | US | disclosed |
| US-8415477-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2013-04-09 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
| WO-2000026262-A2 | FUNCTIONALIZED POLYMERIC SUBSTRATES FOR BINDING MOLECULAR MOIETIES | MITOKOR (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | L3MBTL1 1880/4885GAA 2039/4885MAPT 378/4885 |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | L3MBTL1 1880/4885GAA 2039/4885MAPT 378/4885 |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | L3MBTL1 1880/4885GAA 2039/4885MAPT 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.