Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329216 | 0.83 | MAOB (0.50) | MAOB | |
| SCHEMBL3060051 | 0.80 | MAOB (0.51) | MAOB | |
| SCHEMBL12017499 | 0.80 | NOS1 (0.49) | SLC22A12 | |
| SCHEMBL14021848 | 0.79 | CYP4F2 (0.52) | MAOBCYP4F2CYP4A11 | |
| SCHEMBL9828151 | 0.78 | CYSLTR1 (0.62) | — | |
| SCHEMBL1233624 | 0.77 | SLC22A12 (0.64) | MAOBSLC22A12CYP4F2CYP4A11DRD2 | |
| SCHEMBL3886612 | 0.77 | BCHE (0.49) | MAOBSLC22A12CYP4F2CYP4A11 | |
| SCHEMBL1243217 | 0.76 | RAB9A (0.47) | MAOB | |
| SCHEMBL4674381 | 0.75 | NOS1 (0.41) | MAOB | |
| SCHEMBL3060047 | 0.75 | PARP1 (0.47) | MAOBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356989-B1 | Sulfon amides with a tetrazolyl rest, process for their preparation an therapeutic agents | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5173500-A | Inhibiting thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-22 | — | — | US | disclosed |
| EP-0356989-A2 | Sulfon amides with a tetrazolyl rest, process for their preparation an therapeutic agents | Roche Diagnostics GmbH (DE) | 1990-03-07 | — | — | EP | disclosed |