Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329726 | 0.88 | HTT (0.55) | POLBHTTALDH1A1SMN1; SMN2HDAC3 | |
| SCHEMBL9329706 | 0.87 | MAPK1 (0.52) | POLBHTTALDH1A1CYP2C19MAPT | |
| SCHEMBL9331874 | 0.81 | ALDH1A1 (0.58) | POLBHTTALDH1A1CYP2C19MAPT | |
| SCHEMBL9512641 | 0.79 | POLB (0.62) | POLBGAACMA1GSK3AGSK3B | |
| SCHEMBL9329794 | 0.78 | HTT (0.56) | POLBHTTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9331863 | 0.74 | MAPK1 (0.50) | POLBGSK3AGSK3BHTTALDH1A1 | |
| SCHEMBL9329762 | 0.73 | MAPK1 (0.51) | POLBGSK3AGSK3BHTTALDH1A1 | |
| SCHEMBL9329720 | 0.72 | MAPK1 (0.48) | POLBGSK3AGSK3BHTTALDH1A1 | |
| SCHEMBL1445190 | 0.70 | GAA (0.51) | POLBGAACMA1GSK3AGSK3B | |
| SCHEMBL4003120 | 0.70 | GAA (0.66) | POLBGAACMA1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393109-B1 | NOVEL 2,3-THIOMORPHOLINEDIONE-2-OXIME DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZET (HU) | 1994-03-23 | — | — | EP | disclosed |
| US-5106846-A | Antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1992-04-21 | — | — | US | disclosed |