Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511632 | 0.82 | HTT (0.59) | POLBMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL9514131 | 0.82 | ALDH1A1 (0.60) | MAPTALDH1A1LMNASIGMAR1GRM2 | |
| SCHEMBL9329331 | 0.79 | POLB (0.60) | POLBGAACMA1GSK3AGSK3B | |
| SCHEMBL28958322 | 0.79 | ALDH1A1 (0.50) | POLBALDH1A1GRM2SMN1; SMN2MAPK1 | |
| SCHEMBL9743263 | 0.79 | GRM2 (0.54) | MAPTALDH1A1NPSR1GRM2SMN1; SMN2 | |
| SCHEMBL4182979 | 0.78 | MAPK1 (0.57) | POLBCMA1GSK3AGSK3BMAPT | |
| SCHEMBL28958218 | 0.78 | POLB (0.56) | POLBALDH1A1LMNASIGMAR1TSHR | |
| SCHEMBL11432095 | 0.76 | GAA (0.68) | POLBGAACMA1GSK3AGSK3B | |
| SCHEMBL9743824 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL9741850 | 0.75 | ALDH1A1 (0.49) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320910-B1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZET (HU) | 1993-12-08 | — | — | EP | disclosed |
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | disclosed |